INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
PARK, SEA GWANG,박세광,ROH, KUG HWAN,노국환,KIM, YEON YE,김연예,KIM, HYUN WOONG,김현웅,AHN, KI JUNG,안기정
申请号：
KR1020170071521
公开号：
KR1019064940000B1
申请日:
2017.06.08
申请国别(地区):
KR
年份:
2018
代理人:
摘要：
The present invention relates to a pharmaceutical composition for preventing or treating an angiogenic disease comprising collagen and a pigment epithelial derived factor (PEDF) as an active ingredient. More particularly, the present invention relates to a pharmaceutical composition for preventing or treating an angiogenic disease comprising collagen and PEDF to enable to increase the anti-angiogenic activity cycle of PEDF and extend the dosage range thereof by coadministration of collagen type I and PEDF. Therefore, it is possible to solve a conventional inconvenience problem caused by the frequent injection of PEDF and the side effects thereof, and it can be applied to various angiogenic diseases therapeutic agents.본 발명은 콜라겐 및 색소 상피성 인자(Pigemented Epithelium Derived Factor)를 유효성분으로 함유하는 신생혈관질환 예방 또는 치료용 약학조성물에 관한 것으로, 보다 상세하게는 콜라겐 타입 Ⅰ과 PEDF 병용 투여를 통하여 PEDF의 짧은 항혈관신생 활성주기에 증가시키고, PEDF의 투여 용량 범위를 확장시킬 수 있으므로, 종래의 PEDF 잦은 주입에 따른 불편함과 그에 따른 부작용 문제를 해결할 수 있으며, 다양한 혈관신생질환 치료제로 적용이 가능하다.
