A nose bleed treatment system for use in treating a patient having a nose bleed uses a nose clip that resiliently clamps the patients nostrils to provide pressure to help stop the bleeding. A medically effective agent is sprayed in the patients nostril using a spray bottle that has an elongated tip to apply the agent close to the source of the bleed. The medically effective agent contains at least one of a clot enhancing agent and a vasoconstricting agent. The agent may contain vitamin K as well as a vasoconstricting agent epinephrine with pytonadione (vitamin K1), menaquinone (vitamin K2), menadion (vitamin K3) fibrogen or other suitable medications. The medically effective agents are preferably herbally or mammalian sourced.