GEIERSTANGER, BERNHARD HUBERT,OU, WEIJIA,UNO, TETSUO
申请号：
CA2900755
公开号：
CA2900755A1
申请日:
2014.02.07
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention provides specific sites for modifying antibodies or antibody fragments by replacing at least one native amino acid in the constant region of a parental antibody or antibody fragment with cysteine, which can be used as a site of attachment for a payload or linker-payload combination.
