Burnham Institute for Medical Research;Dana-Farber Cancer Institute, Inc.
发明人:
Marasco, Wayne A.,Sui, Jianhua,Liddington, Robert C.
申请号:
AU2019204310
公开号:
AU2019204310A1
申请日:
2019.06.19
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
#$%^&*AU2019204310A120190711.pdf#####ABSTRACT The invention provides human scFv antibodies and monoclonal antibodies that neutralize influenza virus. The antibodies recognize an epitope in the stem region of the hemaglutinin (HA) protein. Also provided are methods of treating and/or preventing an influenza related disease or disorder such as bird flu. The invention also provides methods of vaccinating a patient against influenza. Also provided are methods of diagnosing influenza-related diseases or disorders and methods of detecting the presence of an influenza in a sample.