您的位置: 首页 > 农业专利 > 详情页

КОМПОЗИЦИЯ В ВИДЕ ПЕРОРАЛЬНОЙ ПЛЕНКИ
专利权人:
ЛАБТЕК ГМБХ (DE)
发明人:
БРАЙТЕНБАХ Армин (DE),ШВИР Нина (DE)
申请号:
RU2012146987/15
公开号:
RU2012146987A
申请日:
2011.04.05
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A pharmaceutical composition comprising at least one triptan and at least one reducing agent comprising a thiol gruppu.2. A pharmaceutical composition according to Claim. 1, wherein the reducing agent containing a thiol group is present in a concentration of from about 0.01 to about 7% by weight, preferably in a concentration of from 0.07 to 6.0% by weight, most preferably in a concentration of from 0 2 to 1.0% by masse.3. A pharmaceutical composition according to Claim. 1 or 2 which contains not more than about 1.0% by weight, preferably not more than 0.9% by weight, most preferably not more than 0.8% by weight triptane decomposition products after as the pharmaceutical composition was subjected to an accelerated stability test (15 days of storage at 60 ° C) .4. A pharmaceutical composition according to Claim. 1 which contains no more than about 1.0%, preferably not more than 0.8% by weight, most preferably less than 0.5% by weight triptane N-oxide after the pharmaceutical composition is subjected to accelerated stability test (15 days of storage at 60 ° C) .5. A pharmaceutical composition according to claim 1, wherein the ratio of the reducing agent comprising a thiol group, a triptan is not more than 2:. 1, in particular not more than 1: 1, preferably not more than 0.5: 1, and most preferably not more than 0.1: 1.6. A pharmaceutical composition according to claim 1, wherein the reducing agent containing a thiol group is selected from the group consisting of glutathione, L-cysteine, dithiothreitol, methionine, thioglycerol, thioglycolic acid, or a pharmaceutically acceptable soley.7. The pharmaceutical composition of claim 1 which comprises the following1. Фармацевтическая композиция, содержащая по меньшей мере один триптан и по меньшей мере один восстанавливающий агент, содержащий тиольную группу.2. Фармацевтическая композиция по п. 1, где восстанавливающий агент, содержащий тиольную группу, присутствует в концентрации от 0,01 до приблизительно 7% по массе, пр
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充