VENKATRAMAN SRIPATHY,MAHMOOD SYED,MOBELE BINGIDIMI I,LAPINA OLGA,VERCOE KELLIE,LI YING,SALSBURY JONATHAN,MCLAWS MARK
申请号：
NZ59889110
公开号：
NZ598891A
申请日:
2010.08.24
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is a method to synthesize a disubstituted piperazines coupled with benzene and nicotinic acid moieties, according to the compounds of formula (I). The method employs piperazine and a substituted nicotinic acid as starting materials and culminates in providing disubstituted piperazine comprising a benzyl substitution at one of the ring nitrogens. The synthesis may further include conversion of this disubstituted piperazine to a suitable salt.
