DONELLO JOHN E,YANG RONG,LEBLOND BERTRAND,BEAUSOLEIL ERIC,CASAGRANDE ANNE-SOPHIE,DESIRE LAURENT J R,PANDO MATTHEW P,CHAUVIGNAC CEDRIC,TAVERNE THIERRY
申请号:
ZA201306416
公开号:
ZA201306416B
申请日:
2013.08.26
申请国别(地区):
ZA
年份:
2014
代理人:
摘要:
The invention relates to compounds of the formula wherein R′, R1, through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.