GARY PHILLIPS,JENNIFER A. TREIBERG,JERRY EVARTS,JOSHUA KAPLAN,JOSHUA VAN VELDHUIZEN,LEENA PATEL,MUSONG KIM,STEPHANE PERREAULT
申请号：
BR112015031475
公开号：
BR112015031475A2
申请日:
2014.06.13
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
The present disclosure provides phosphatidylinositol 3-kinase (PI3K) inhibitors of formula (I), or pharmaceutically acceptable salts or isomers thereof, in which n, m, R1, R2, R4, and R3 are as defined herein. These compounds are useful for treatment of conditions mediated by one or more PI3K isoforms, such as PI3K&delta；. The present disclosure further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts or isomers thereof, and methods of using these compounds and compositions to treat conditions mediated by one or more PI3K isoforms, such as PI3K&delta；.
