Lewis Cantley;Matthew G. Vander Heiden;Heather R. Christofk
发明人:
Lewis Cantley,Matthew G. Vander Heiden,Heather R. Christofk
申请号:
US12376285
公开号:
US08877791B2
申请日:
2007.08.06
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention provides pharmaceutical compositions, kits, and methods of treating cancer, diabetes, obesity, autoimmune disease, and benign prostatic hyperplasia using compounds that selectively inhibit pyruvate kinase M2 and an assay measuring chemical modulation of pyruvate kinase activity.