The invention relates to a prosthetic heart valve (100) for an endoprosthesis (1) used in the treatment of a stenotic cardiac valve and/or a cardiac valve insufficiency. The prosthetic heart valve (100) comprises of a plurality of leaflets (102), which consist of a natural and/or synthetic material and have a first opened position for opening the heart chamber and a second closed position for closing the heart chamber, the leaflets (102) being able to switch between their first and second position in response to the blood flow through the heart. In addition, the prosthetic heart valve (100) comprises a leaflet support portion (103), consisting of biological and/or synthetic material for mounting of the prosthetic heart valve (100) to a stent (10), and a bendable transition area (104) which forms a junction between the leaflets (102) and the leaflet support portion (103), the transition area (104) progressing essentially in a U-shaped manner similar to a cusp shape of a natural aortic or pulmonary heart valve for reducing tissue stresses during opening and closing motion of the leaflets (102). The invention further relates to an endoprosthesis (1) comprising a prosthetic heart valve (100) and a stent (10)【解決手段】本発明は、心臓弁狭窄および/または心臓弁不全症の治療に用いられる体内プロテーゼ(1)用の人工心臓弁(100)に関する。人工心臓弁(100)は、自然組織および/または合成材料からなり、心腔を開く第1の開位置と心腔を閉じる第2の閉位置とを有する複数の弁尖(102)であって、心臓を通る血流に応じて第1の位置と第2の位置の間を行き来する弁尖(102)を備える。加えて、人工心臓弁(100)は、人工心臓弁(100)をステント(10)に取り付けるための自然組織および/または合成材料からなる弁尖支持部(103)と、弁尖(102)と弁尖支持部(103)の間の接合部を形成する屈曲可能な移行領域(104)と、を備える。屈曲可能な移行領域(104)は、生体大動脈弁または肺動脈弁の弁尖形状と同様に本質的にU字形に進み、弁尖(102)の開閉動作中の組織応力を低減する。本発明はさらに、人工心臓弁(100)とステント(10)を備える体内プロテーゼ(1)に関する。【選択図】図11a
