The invention relates to a compound represented by the following formula (I): and pharmaceutically acceptable salts, stereoisomers, enantiomers, prodrugs and solvates thereof. The compounds are useful as an agent for enhancing the neurite outgrowth and preventing or treating of diseases associated with HDAC in particular, tumor or cell proliferative diseases. In particular, the compounds of the invention can be used as an agent for anti-neurodegenerative diseases and human spinal muscular atrophy (SMA).本發明係關於由下式(I)代表的化合物：及其醫藥上可接受之鹽、立體異構物、鏡像異構物、前藥及溶劑化物。該等化合物可作為增強神經突觸生長及預防或治療與組織蛋白去乙醯酶(HDAC)有關疾病(尤其是腫瘤或細胞增殖疾病)的藥劑；彼等亦可作為促進神經生長的藥劑。特別地，本發明化合物可作為抗神經退化疾病及脊髓肌肉萎縮症(SMA)的藥劑。
