CHIUEH, CHUANG CHUN,阙壮群,闕壯群,LEE, CHUN NAN,李君男,李君男,CHENG, CHUN TING,郑钧霆,鄭鈞霆
申请号：
TW097130505
公开号：
TWI359669B
申请日:
2008.08.11
申请国别(地区):
TW
年份:
2012
代理人:
摘要：
The present invention provides a pharmaceutical composition for treating rotavirus and/or respiratory syncytial virus infection and a method for preparing the same wherein said pharmaceutical composition comprises a therapeutically effective amount of Spirulina extract and a pharmaceutically acceptable carrier. The Spirulina extract used in the present invention is extracted at a low temperature by the following steps: (a) adding an organic Spirulina powder into a hypotonic buffer solution and mixed well to obtain a mixture (b) freezing the mixture from step (a) overnight at a temperature lower than 0° C. (c) thawing the mixture from step (b) (d) separating and purifying the mixture from step (c) by a separator, and collecting blue fractions and (e) spray drying the blue fractions from step (d).本發明係提供一種用於治療輪狀病毒及/或呼吸道融合病毒感染之醫藥組合物及其製備方法,其中前述醫藥組合物係包含一治療有效量的藍藻(Spirulina)萃取物及一醫藥可接受之載體。本發明所用之藍藻萃取物係在低溫萃取而得,其步驟包含:(a)有機藍藻粉加入低張緩衝液,充分攪拌均勻;(b)0℃以下靜置過夜;(c)靜置解凍;(d)分離機分離純化,收集藍色分液;及(e)噴霧乾燥。
