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Method of Fabricating Anticancer Drug Having Doxorubicin Bonded with Gold Nanoparticles
专利权人:
发明人:
Chun-Chia Cheng,Tsai-Yueh Luo
申请号:
US14672711
公开号:
US20160287723A1
申请日:
2015.03.30
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Albumin and doxorubicin are bonded through reaction. The bonded albumin and doxorubicin are added with a gold-nanoparticles solution for reaction. After being purified with water in a column, the liquid phase of gold-nanoparticles is changed into a phosphate buffer for obtaining an anticancer drug having doxorubicin bonded with gold nanoparticles. Thus, with the high biocompatibility and the big surface areas, gold nanoparticles are used in biological applications and used as carriers for increasing drug accumulation on tumor. The bonding between gold nanoparticles and doxorubicin increases stability of doxorubicin. Besides, doxorubicin has tumor-killing effect for cancer therapy.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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