Evelyn M. McKeegan,Barry L. Dowell,Richard R. Lesniewski,Dimitrí Semizarov
申请号：
US13311752
公开号：
US08748108B2
申请日:
2011.12.06
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Disclosed are methods for classifying a patient with cancer as a candidate for therapy with a Bcl-2 family inhibitor comprising determining the level of at least one biomarker in a sample and comparing the biomarker level to a threshold level. Also described are methods for identifying classes of patients having a refractory cancer for second-line therapy comprising a Bcl-2 family inhibitor, where the method comprises determining the level of at least one biomarker in a sample and comparing the biomarker level to a threshold level.
