The Walter and Eliza Hall Institute of Medical Research
发明人:
Cowman, Alan,Chen, Lin,Baum, Jacob
申请号:
AU2009287420
公开号:
AU2009287420B2
申请日:
2009.08.27
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
This invention relates to an immunogenic molecule comprising a contiguous amino acid sequence of an invasion ligand of a strain of Plasmodium falciparum, the invasion ligand capable of binding to an erythrocyte receptor, the receptor function being resistant to trypsin and neuraminidase and chymotrypsin, wherein when administered to a subject the molecule is capable of inducing an immune response to the strain. The invention further relates to compositions and methods for the treatment of diseases such as malaria.