STUMBER, MICHAEL, DR.,Michael, Dr. Stumber,TEEFFELEN, KATHRIN VAN, DR.,Kathrin van, Dr. Teeffelen,HORTON, MARGARET,Margaret Horton,HOFFMANN, NILS,Nils Hoffmann
申请号：
DE102010063895
公开号：
DE102010063895A1
申请日:
2010.12.22
申请国别(地区):
DE
年份:
2012
代理人:
摘要：
Die Erfindung bezieht sich auf Mikrokörper (14) insbesondere aus Silizium oder Silizium enthaltend und ein Verfahren zum Transport mindestens eines Wirkstoffes (28) in die Epidermis. Die Mikrokörper (14) sind entweder porös geätzt zur Einlagerung mindestens eines Wirkstoffes (38) oder sind als schwammartige Struktur ausgeführt, in der mindestens ein Wirkstoff (38) eingelagert ist.Microporous body (14) preferably from or containing silicon, for the local treatment of skin, preferably aging such as wrinkling or for application of active agents (38) in age spots or hyperpigmentation of the skin, is claimed, where the microporous body exhibits etched porous and pores (36) for storing at least one active agent, or formed in the from of sponge-like structure whose pores are embedded with the active substance. Independent claims are included for: (1) the preparation of microbody comprising (a) preparing an array of microbody, which are anchored on the carrier material by a structuring process, (b) generating the predetermined breaking points (26, 28) between the microbody and the carrier material, (c) generating a porous and/or sponge-like structure of the microbody, and (d) storing the active ingredient in the pores of the microbody and (2) transporting the active ingredient into the epidermis, preferably in skin layers below the stratum corneum comprising storing the active ingredient in pores or a pore structure of the porous microbody having at least one sharp-edge structure (16), which are replaced by the application of rotation or shearing motions of the carrier material. ACTIVITY : Dermatological Antiseborrheic Antiinflammatory Insect Repellent. MECHANISM OF ACTION : None given.
