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取代的4-氨基環己衍生物
- 专利权人:
- GRUNENTHAL GMBH
- 发明人:
- NOLTE, BERT,SCHRDER, WOLFGANG,LINZ, KLAUS,ENGLBERGER, WERNER,SCHICK, HANS,GRAUBAUM, HEINZ,BRAUN, BIRGIT,OZEGOWSKI, SIGRID,BLINT, JZSEF,SONNENSCHEIN, HELMUT
- 申请号:
- HK11103313.1
- 公开号:
- HK1149257B
- 申请日:
- 2011.04.01
- 申请国别(地区):
- HK
- 年份:
- 2014
- 代理人:
- 摘要:
- Substituted 4-aminocyclohexane derivatives (I) and their stereoisomers or their mixtures, free compounds and/or salts are new, where (I) excludes 4-(dimethylamino)-1-methyl-4-p-tolylcyclohexyl acetate. Substituted 4-aminocyclohexane derivatives of formula (I) and their stereoisomers or their mixtures, free compounds and/or salts are new, where (I) excludes 4-(dimethylamino)-1-methyl-4-p-tolylcyclohexyl acetate. Either Y 1>;, Y1a, Y 2>;, Y2a, Y 3>;, Y3a, Y 4>;, Y4a : H, F, Cl, Br, I, CN, NO 2, CHO, R 0>;, C(=O)R 0>;, C(=O)H, -C(=O)-OH, -C(=O)OR 0>;, C(=O)NH 2, C(=O)NHR 0>;, C(=O)N(R 0>;) 2, OH, OR 0>;, -OC(=O)H, -OC(=O)R 0>;, -OC(=O)OR 0>;, -OC(=O)NHR 0>;, -OC(=O) N(R 0>;) 2, -SH, -SR 0>;, -SO 3H, -S(=O) 1 - 2-R 0>;, -S(=O) 1 - 2NH 2, -NH 2, -NHR 0>;, -N(R 0>;) 2, -N +>;(R 0>;) 3, -N +>;(R 0>;) 2O ->;, -NHC(=O)R 0>;, -NHC(=O)OR 0>;, NHC(=O)-NH 2, -NHC(=O)-NHR 0>;or -NHC(=O)N(R 0>;) 2, preferably -H, -F, -Cl, -CN or 1-8C-aliphate; or Y 1>;Y1a, Y 2>;Y2a, Y 3>;Y3a, Y 4>;Y4a : (=O); Q : R 0>;, -C(=O)-R 0>;, -C(=O)OR 0>;, -C(=O)NHR 0>;, -C(=O)N(R 0>;) 2or -C(=NH)-R 0>;; R 0>; : 1-8C-aliphate, 3-12C-cycloaliphate, aryl, heteroaryl, 1-8C-aliphate-3-12C-cycloaliphate, 1-8C-aliphate-aryl, 1-8C-aliphate-heteroaryl, 3-8C-cycloaliphate-1-8C-aliphate, 3-8C-cycloaliphate-aryl or -3-8C-cycloaliphate-heteroaryl, where the: aliphate is optionally saturated, optionally substituted aliphatic hydrocarbon, cycloaliphate is optionally saturated, optionally substituted alicyclic, mono- or multicyclic 3-8C-hydrocarbon (where the H atoms of the aliphate or cycloaliphate are one or more times substituted by F, Cl, Br, I, CN, -NO 2, -CHO, =O, -R 0>;, -C(=O)R 0>;, -C(=O)H, -C(=O)OH, -C(=O)OR 0>;, -C(=O)NH 2, -C(=O) NHR 0>;, -C(=O)N(R 0>;) 2, -OH, -OR 0>;, -OC(=O)H, -OC(=O)R 0>;, -OC(=O)OR 0>;, -OC(=O)NHR 0>;, -OC(=O)N(R 0>;) 2, -SH, -SR 0>;, -SO 3H, -S(=O) 1 - 2-R 0>;, -S(=O) 12NH 2, -NH 2, -NHR
- 来源网站:
- 中国工程科技知识中心
- 来源网址:
- http://www.ckcest.cn/home/