Disclosed is a seamless capsule comprising a liquid pharmaceutically active ingredient and one or more kinds of solid pharmaceutically active ingredients, wherein the liquid pharmaceutically active ingredient is encapsulated in the form of a liquid pharmaceutical composition, and the solid pharmaceutically active ingredient is dispersed in a capsule shell layer, the liquid pharmaceutically active ingredient comprises a ù3-fatty acid ethyl ester, the ù3-fatty acid ethyl ester comprises EPA ethyl ester and DHA ethyl ester, and the liquid pharmaceutical composition comprises not less than 40 percent w/w of EPA ethyl ester and not less than 34 percent w/w of DHA ethyl ester, and the capsule shell layer is formed by a shell composition comprising glycerin and sorbitol.
