ELORANTA MAIRE,HIRVELÄ LEENA,KANGAS LAURI,KOSKIMIES PASI,LAMMINTAUSTA RISTO,UNKILA MIKKO
申请号：
IN11723/DELNP/2015
公开号：
IN2015DN11723A
申请日:
2015.12.23
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof wherein R2to R7are as defined in the claims. The invention further relates to their use as inhibitors of 17ß- HSD and in treatment or prevention of steroid hormone de- pendent diseases or disorders, such as steroid hormone dependent diseases or disorders requiring the inhibition of the 17ß- HSD1 enzyme and/or requiring the lowering of the endogenous estradiol concentration. The present invention also relates to the preparation of the aforementioned compounds and to pharmaceutical compositions comprising as an active ingredient(s) one or more of the afore - mentioned compounds or pharmaceutically acceptable salts thereof.
