４－（４－（１－異丙基－７－側氧基－１，４，６，７－四氫螺〔吲唑－５，４’－哌啶〕－１’－羰基）－６－甲氧基吡啶－２

发明人:: FERNANDO, DILINIE PRASADHINI,法兰度　迪林尼,法蘭度　迪林尼,LACASSE, SHAWN M.,拉柯赛　尚恩,拉柯賽　尚恩,WIGLESWORTH, KRISTIN,威格勒　克里斯汀

摘要：: The invention provides the tris salt of 4-(4-(1-isopropyl-7-oxo-1,4,6,7-tetrahydrospiro[indazole-5,4'-piperidine]-1'-carbonyl)-6-methoxypyridin-2-yl)benzoic acid as a crystalline anhydrous or tri-hydrate； as well as polymorphs, pharmaceutical compositions, dosage forms, and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of an acetyl-CoA carboxylase (ACC) enzyme(s) in an animal.本發明提供4-(4-(1-異丙基-7-側氧基-1,4,6,7-四氫螺[吲唑-5,4’-哌啶]-1’-羰基)-6-甲氧基吡啶-2-基)苯甲酸之tris鹽作為結晶無水或三水合物；以及多晶型、醫藥組成物、劑型，以及其用於治療動物由抑制乙醯輔酶A羧化酶(acetyl-CoA carboxylase，ACC)酵素所調節之疾病(disease)、狀況(condition)或病症(disorder)的用途。