Mark J. Bartlett,Julian Andrew Codelli,Britton Kenneth Corkey,Jennifer Leigh Cosman,Kristyna Elbel,Jennifer Alissa Loyer-Drew,David Sperandio,Joshua Van Veldhuizen,Hai Yang,Suet Chung Yeung
申请号:
US15153527
公开号:
US20160333009A1
申请日:
2016.05.12
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure provides indoleamine 2,3-dioxygenase 1 (IDOL) inhibitors of Formula I:or pharmaceutically acceptable salts thereof, in which X, L, n, m, R1, R2a, R2b, Rn, Rm, and Rt are as defined herein, as well as pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using the same to treat conditions mediated by IDO1.