The present application relates to activable inorganic nanoparticles which can be used in the health sector, in particular in human health, to disturb, alter or destroy target cancerous cells, tissues or organs. It more particularly relates to nanoparticles which can generate a surprisingly efficient therapeutic effect, when concentrated inside the tumor and exposed to ionizing radiations. The invention also relates to pharmaceutical compositions comprising a population of nanoparticles as defined previously, as well as to their uses.本申請案係關於可活化無機奈米粒子,其可用於健康方面、尤其人類健康中以擾亂、改變或破壞靶標癌細胞、組織或器官。本發明更尤其係關於在腫瘤內側濃集並暴露於離子化輻射時可生成極高效的治療效應之奈米粒子。本發明亦係關於包含如上文所定義之奈米粒子群之醫藥組合物,以及其用途。