Hong Guan Ltd.;Peking University;Beijing Vitalstar Biotechnology Co., Ltd.
发明人:
申请号：
EP15843227.8
公开号：
EP3198004A4
申请日:
2015.09.18
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Provided is a cocktail of factors for converting/reprogramming non-naïve pluripotent stem cells into TGFβ signaling-independent (TSI) naïve induced pluripotent stem cells (iPSCs). Also provided are methods for reprograming a non-naïve PSC into a TSI naïve iPSC by contacting the cell to be reprogrammed with effective amounts of compounds for a sufficient period of time to reprogram the cell into a TSI naïve iPSC.
