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MICROPARTICULES CHARGEES EN CYCLOSPORINE A LIBERATION PROLONGEE
专利权人:
MIDATECH PHARMA (WALES) LIMITED
发明人:
SEAMAN, PAUL,BAMSEY, KATHARINE,THOMAS, NIGEL,PAICE, DEWI
申请号:
CA3008491
公开号:
CA3008491A1
申请日:
2016.12.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
A controlled release pharmaceutical formulation is provided, comprising cyclosporine-loaded microparticles of a bioresorbable polymer comprising poly(D,L-lactide), wherein the mean diameter of the microparticles is in the range 20 µm to 40 µm. Also provided are medical uses of the pharmaceutical formulation, in particular in the treatment of uveitis, a process for production of the pharmaceutical formulation and injectable dosage forms, including those formulated for intravitreal injection.
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