Novel polypeptides comprising a chemokine-binding peptide and an Fc fragment are disclosed. The polypeptides are capable of binding to certain chemokines so as to modulate their activity. These polypeptides can be used to modulate in vivo chemokine-dependent processes such as inflammation and autoimmunity, and to treat associated conditions.L'invention porte sur de nouveaux polypeptides comprenant un polypeptide fixant la chémokine et un fragment de Fc. Lesdits polypeptides peuvent se fixer à certaines chémokines pour en moduler lactivité, et donc moduler in vivo certains processus dépendants de la chémokine, tels que linflammation et lauto-immunité, et traiter les états associés.
