DISPOSITIF POUR DÉTECTER ET DÉTRUIRE DES CELLULES TUMORALES INDIVIDUELLES, DES AGRÉGATS DE CELLULES TUMORALES ET DES MICROMÉTASTASES DANS LA CIRCULATION SANGUINE.
The present invention relates to a device for registering individual tumour cells, tumour cell clusters and micrometastases in the bloodstream which are enriched with a photosensitive substance. The problem addressed by the invention is that of providing a device that enables both the reliable diagnostic recognition of individual tumour cells in the bloodstream of humans and mammals and also the therapeutic in situ elimination of same. This problem is solved with a device that has a radiation source (7, 11) with intravasal or extravasal excitation of the photosensitive substance, a detector (1, 12, 13) with intravasal or extravasal detection of a fluorescence and/or phosphorescence and/or luminescence radiation of the excited tumour cells and/or tumour cell clusters and/or micrometastases, a high-sensitivity fluorescence spectrometer (5) connected to the detector (1, 12, 13) for registering the emitted radiation, and a computer (6) connected to the spectrometer (5), which records the received peaks of the emitted radiation as a function of time.
