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PHARMACEUTICAL DOPAMINE GLYCOCONJUGATE COMPOSITIONS AND METHODS OF THEIR PREPARATION
专利权人:
INTERNATIONAL MEDICAL INNOVATIONS INC.
发明人:
CHRISTIAN, SAMUEL, T.
申请号:
HK04105634.7
公开号:
HK1063186B
申请日:
2004.07.30
申请国别(地区):
HK
年份:
2012
代理人:
摘要:
Hydrophilic transportable N-linked glycosyl dopaminergic prodrug compounds according to FORMULA V,wherein, Ring 1 comprises a cyclic or heterocyclic ring, or aryl or heteroaryl ring, all of said rings comprising 4 to 8 carbon atoms, among which atoms are counted "X" and "Y" R0, R1, R2, R3 and R4 comprise substituents of Ring 1 either of X or Y is optional each of X and Y, when present comprise a carbon atom, a halogen atom or a lower alkyl Z, R5 and R5 are optional when Z is present it comprises a lower alkyl having substituents R5, R5 R6 and R6 comprise substituents on a carbon atom linking Z with N through a single bond, or when Z is absent, linking N with Ring 1 N comprises a nitrogen atom of an amine or an amide linked with E through a single bond and having R7 as a substituent and E comprises a saccharide.
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