KUANG, JINQIANG,ALLA, DANILKOVITCH,MARCONI, JENNIFER MICHELLE,JANSEN, TIMOTHY,SAMSON, TOM,DANA YOO
申请号:
ARP110100506
公开号:
AR080219A1
申请日:
2011.02.18
申请国别(地区):
AR
年份:
2012
代理人:
摘要:
Products include a inmunocompatible placental chorionic membrane. These products may contain criopreservarse placental cells and viable Therapeutic once thawed. The placental products of this are helpful to promote Healing. A method to provide stem cells in a tissue of a subject.The Product can be applied on placental is graft. Claim 1: a method to manufacture a placental product, characterized in that it comprises the following steps: to obtain a placenta; B. selectively remove a substantial portion of one or more types of cells of the chorionic Membrane immunogen, where I.The one or more cell types include immunogenic Trophoblasts, CD14 + macrophages or macrophage CD14 + Functional Trophoblasts and functional; and II. The step of selective Removal does not Exterminate or remove substantially all of Therapeutic cells, which are selected from the MSC, fibroblasts or a combination of these; and C.The chorionic Membrane cryopreservation cryopreservation in a medium; and D. optionally remove substantially all of the tissue or cells immunogenic vascularized Tissue derived vascular placental or chorionic membrane.Productos placentarios que comprenden una membrana corionica inmunocompatible. Estos productos placentarios pueden criopreservarse y contienen células terapéuticas viables una vez descongelados. Los productos placentarios de la presente son utiles para promover la cicatrizacion. Un método para proveer células madres en un tejido de un sujeto. El producto placentario se puede aplicar sobre es injerto. Reivindicacion 1: Un método para manufacturar un producto placentario, caracterizado porque comprende los siguientes pasos: a. obtener una placenta; b. eliminar selectivamente una porcion sustancial uno o más tipos de células inmunogénicas de la membrana corionica, donde i. los uno o más tipos de células inmunogénicas comprenden trofoblastos, macrofagos CD14+ funcionales o trofoblastos y macrofagos CD14+ funcionales; y ii. el paso de eliminacion selectiva no compren