METHODES ET COMPOSITIONS D'IMMUNOTHERAPIE CELLULAIRE

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专利权人:

INC.;EFFECTOR THERAPEUTICS

发明人:

WEBSTER, KEVIN R.,SHARMA, RAJESH,CHIANG, GARY

申请号：

CA3064000

公开号：

CA3064000A1

申请日:

2018.05.24

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present disclosure relates to genetically modified T cells comprising a transgene encoding an engineered antigen specific receptor, wherein expression of an endogenous gene selected from MNKl, MNK2, or both are inhibited in the genetically modified T cell in order to enhance central memory T cell subsets in cellular immunotherapy compositions.

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中国工程科技知识中心

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http://www.ckcest.cn/home/