A syringe system (100) is provided. The syringe system comprises a pump assembly (101) including a movable actuation rod (440) and a plunger contact (445) coupled to an end of the movable actuation rod (440). The syringe system also comprises a cartridge assembly (102). The cartridge assembly (102) includes a manifold (105) removably coupled to the pump assembly (101) and a syringe cartridge (107) positioned within the manifold (105) and including a plunger assembly (330) movable with respect to the manifold (105) upon actuation of the actuation rod (440).