Composition and method for suppressing expression of JC virus gene

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专利权人:

ファーマシューティカルズ，;インコーポレイテッド;アルナイラム;アルナイラム ファーマシューティカルズ, インコーポレイテッド

发明人:

パメラ タン,ディナ サー,ビルギット ブラムレイジ

申请号：

JP2011066818

公开号：

JP5398769B2

申请日:

2011.03.24

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the JC Virus (JC virus genome), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part of a gene from the JC Virus. The invention also relates to a pharmaceutical composition comprising the dsRNA together with a pharmaceutically acceptable carrier； methods for treating diseases caused by JC virus expression and the expression of a gene from the JC Virus using the pharmaceutical composition； and methods for inhibiting the expression of a gene from the JC Virus in a cell.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/