Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells

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专利权人:

Glycovaxyn AG

发明人:

Wacker, Michael,Waechter, Charles

申请号：

AU2010322454

公开号：

AU2010322454A1

申请日:

2010.11.16

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

The invention is directed to bioconjugate vaccines comprising -glycosylated proteins. Further, the present invention is directed to a recombinant prokaryotic biosynthetic system comprising nucleic acids encoding an epimerase that synthesizes an oligo- or polysaccharide having-acetylgalactosamine at the reducing terminus. The invention is further directed to -glycosylated proteins containing an oligo- or polysaccharide having -acetylgalactosamine at the reducing terminus and an expression system and methods for producing such glycosylated proteins.

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中国工程科技知识中心

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