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6-arylalkylamino-2,3,4,5-tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonists
专利权人:
Karen Briner;John Cunningham O'Toole;Christopher Stanley Galka;Michael Philip Mazanetz;Marta Adeva Bartolome;Maria Angeles Martinez-Grau;Manuel Javier Cases-Thomas;Alicia Marcos Llorente;Richard Edmun
发明人:
Karen Briner,Manuel Javier Cases-Thomas,Marta Adeva Bartolome,Christopher Stanley Galka,Alicia Marcos Llorente,Maria Angeles Martinez-Grau,Michael Philip Mazanetz,John Cunningham O'Toole,Richard Edmun
申请号:
US13156575
公开号:
US08680091B2
申请日:
2011.06.09
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula (I) as selective 5-HT2c receptor agonists for the treatment of 5-HT2c associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety, where, R6 is —NR10R11, where R10 is substituted phenylalkyl or substituted pyridylalkyl and other substituents are as defined in the specification.
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中国工程科技知识中心
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