3- (benzylamino) -pyrrolidine derivatives and their application as nk-3 receptor antagonists

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专利权人:

F. Hoffmann-La Roche AG

发明人:

Caterina Bissantz,Claus Riemer,Hasane Ratni,Henner Knust,MATTHIAS NETTEKOVEN,Philippe Jablonski

申请号：

BRPI0921788

公开号：

BRPI0921788A2

申请日:

2009.10.26

申请国别(地区):

BR

年份:

2018

代理人:

摘要：

The present invention relates to a compound of formula I wherein Ar, R1, R2, R3, n, and o are as defined herein or to a pharmaceutically active salt, a racemic mixture, an enantiomer, an optical isomer or a tautomeric form thereof. The present compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).

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