PLASMA-TREATED PROTEIN AQUEOUS SOLUTION, PROTEIN FIXED SURFACE EXCELLENT IN CELL AND TISSUE ENGRAFTMENT PROPERTIES WHICH IS PRODUCED USING THE SAME, AND APPLICATIONS THEREOF
PROBLEM TO BE SOLVED: To provide a means of facilitating dramatically improving the biocompatibility of the surfaces of a medical equipment, material, and the like.SOLUTION: The invention relates to a method for dramatically improving cell or biological tissue engraftment properties in a sessile part, the method comprising applying a low-temperature plasma discharge generated from a creeping discharger to protein aqueous solution in a provided area for introducing protein aqueous solution； subjecting a protein containing an extracellular matrix protein to a plasma treatment by the low-temperature plasma discharge, and fixing the protein aqueous solution obtained thereby as mist or droplet on the surface of a metal or hydrophobic polymer, such as a stent.SELECTED DRAWING: Figure 3【課題】医療用の器具や材料等の表面の生体親和性を飛躍的に向上させることを容易化する手段の提供。【解決手段】タンパク質水性溶液の導入場が設けられ、当該導入場においてタンパク質水性溶液に沿面放電体から発生する低温プラズマ放電を作用させることにより、細胞外マトリックスタンパク質を含むタンパク質に対して低温プラズマ放電によるプラズマ化を行い、これにより得られたタンパク質水性溶液を、ミスト又は液滴として、ステント等金属や疎水性ポリマーの表面に定着させることにより、当該定着部分における細胞や生体組織の生着性が飛躍的に向上する方法。【選択図】図３
