GUELCHER, Scott A.,MCGOUGH, Madison A.P.,GUPTA, Mukesh K.,DUVALL, Craig L.,MARTIN, John R.,PAGE, Jon
申请号：
EP16856340
公开号：
EP3362107A4
申请日:
2016.10.14
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
A biodegradable scaffold, a low-molecular weight thioketal, and a method of forming a biodegradable scaffold are provided. The biodegradable scaffold includes a thioketal and an isocyanate, where the thioketal is linked to the isocyanate to form the scaffold. The low-molecular weight thioketal includes 2,2-dimethoxypropane and thioglycolic acid, wherein the thioketal includes at least two hydroxyl terminal groups. The method of forming the biodegradable scaffold includes blending a thioketal with an excess isocyanate, forming a quasi-prepolymer, mixing the thioketal, the quasi-prepolymer, and a ceramic, and then adding a catalyst to form the biodegradable scaffold. The thioketal is a low-molecular weight thioketal having at least two hydroxyl terminal groups.
