INDUSTRY ACADEMIC COOPERATION FOUNDATION; DAEGU UNIVERSITY
发明人:
KANG, SUN CHULKR,강선철
申请号：
KR1020140173099
公开号：
KR1020160067558A
申请日:
2014.12.04
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a health functional food, a cosmetic composition, and a pharmaceutical composition for preventing or improving inflammatory diseases which contain Morin (2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one), its salts, or Morin hydrates as active components. Morin (2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one), its salts, or Morin hydrates as active components of the present invention are effective in preventing and improving inflammation, are safe to the human body as natural derived materials, and are free of side effects although they are used for a long period of time by suppressing production of TNF&alpha, IL-1&beta or Prostaglandin E2 (PGE2) causing inflammation, and suppressing self-predation action. Accordingly, Morin (2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one), its salts, or Morin hydrates as active components of the present invention are useful in inflammation relief and treatment.COPYRIGHT KIPO 2016본 발명은 모린(Morin, 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one), 이의 염 또는 모린 수화물(Morin hydrate)을 유효성분으로 함유하는 염증성 질환의 예방 또는 개선용 건강기능식품, 화장료 조성물 및 약학 조성물에 관한 것이다.본 발명의 유효성분인 모린(Morin, 2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one), 이의 염 또는 모린 수화물(Morin hydrate)은 염증을 유발하는 TNFα, IL-1β 또는 프로스타그란딘 E2(PGE2)의 생성 억제, 및 자기포식 작용을 억제함으로써, 염증의 예방 및 개선에 효과가 있으며, 천연 유래의 물질로 인체에 안전하며 장기간 사용하여도 부작용이 없기 때문에, 염증 완화 및 치료에 유용하다.
