An IOP monitoring device for implantation in an eye of a patient may include a first tube having a first opening, the first tube being configured to extend into an anterior chamber of the eye and extend to a first sensor outside the anterior chamber. The first sensor may be in fluid communication with the first opening of the first tube. The device also may include a second tube having an opening spaced from a second sensor. The opening of the second tube may be configured to be exposed to a pressure representative of atmospheric pressure, with the second sensor being in fluid communication with the second opening. In one aspect, a patch is attachable to a globe of the eye and configured to lie over the opening of the second tube and secure the opening in place in the eye.