Dominique Lemoine;Pierre Michel Desmons;Jan Poolman;Dominique Boutriau;Carine Capiau
发明人:
Dominique Boutriau,Carine Capiau,Pierre Michel Desmons,Dominique Lemoine,Jan Poolman
申请号：
US13439829
公开号：
US09233151B2
申请日:
2012.04.04
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A multi-valent vaccine composition is described comprising a conjugate of the capsular polysaccharide of H. influenzae b not adsorbed onto an aluminum adjuvant salt, and two or more further bacterial polysaccharides. A multi-valent vaccine composition is also described comprising a whole-cell pertussis component, tetanus toxoid, diphtheria toxoid, Hepatitis B surface antigen, a conjugate of the capsular polysaccharide of H. influenzae b, and a conjugate of a capsular polysaccharide of N. meningitidis type A or C (or both). Furthermore, a multi-valent vaccine composition is described comprising a whole-cell pertussis component, tetanus toxoid, diphtheria toxoid, and a low dose of a conjugate of the capsular polysaccharide of H. influenzae b.
