In a method for computer-assisted configuration of a medical imaging device for examination of a patient, training data are provided that include multiple variants of protocols in the form of protocol parameter sets for operation of the imaging device. The training data also include patient-specific parameter sets with one or more features of a patient, the patient-specific parameter sets being associated with the respective protocol parameter sets. Based on the training data, relations between the protocol parameter sets and the patient-specific parameter sets are learned with a data-driven leaning method and stored as patterns in a knowledge base. In an application phase, a protocol parameter set suitable for the examination of the patient can be determined with the use of the patterns in the knowledge base, depending on features of a patient that are provided to the imaging device.
