ZELKHA, MORRIS,LEVY, RACHEL,PARAN, ESTHER,SHARONI, YOAV,LEVY, JOSEPH
申请号：
CA2749202
公开号：
CA2749202C
申请日:
2010.01.19
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention provides use of a combination of carnosicacid and two or more carotenoids selected from the groupconsisting of lutein, lycopene and beta-carotene for thetreatment of inflammation in a mammalian subject. Each of thecarnosic acid and carotenoids may be for administration in adaily amount in the range of 1 to 5 mg. In some embodiments,the carnosic acid and carotenoids are present in the followingweight ratio range for lycopene:lutein:beta-carotene:carnosicacid of 0.1-1.0:0.1-1.0:0.1-1.0:0.1-1Ø In some embodiments,the mammalian subject has a condition selected from the groupconsisting of rheumatoid arthritis, adult respiratory distresssyndrome (ARDS), asthma, rhinitis, idiopathic pulmonaryfibrosis, peritonitis, cardiovascular inflammation, myocardialischemia, reperfusion injury, atherosclerosis, sepsis, trauma,diabetes type II, retinopathy, psoriasis, gastrointestinalinflammation, cirrhosis, peritonitis and inflammatory boweldisease, and neurodegenerative diseases.
