The present invention is directed to novel lyophilized pharmaceuticalpreparations comprising acytotoxic dipeptides such as melphalan flufenamide and one or moreexcipient(s) selected from thegroup comprising a polysorbate； a polyethylene glycol； .beta.-cyclodextrin；ocyclodextrin；hydroxypropyl-.beta.-cyclodextrin； sulfobutylether-.beta.-cyclodextrin；lactose； benzyl alcohol； disodium succinate；propylene glycol； Cremophor EL； Dimethyl sulfoxide； D-mannitol； Trehalose；Sucrose and an aminoacid. This preparation may be further formulated and is useful in cancertherapy.
