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COMPOSITIONS ANESTHESIQUES A LIBERATION PROLONGEE ET LEURS PROCEDES DE PREPARATION
专利权人:
TLC BIOPHARMACEUTICALS, INC.;TAIWAN LIPOSOME CO. LTD.
发明人:
HONG, KEELUNG,TSENG, YUN-LONG,LAI, CHUN-YEN,YU, WAN-NI,KAO, HAO-WEN,LIN, YI-YU
申请号:
CA3095571
公开号:
CA3095571A1
申请日:
2019.03.30
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Provided is an anesthetic composition for locally administering a local anesthetic agent to a subject in need thereof. The anesthetic composition has a lipid based complex prepared by hydrating a lipid cake containing a local anesthetic agent and a lipid mixture with an aqueous buffer solution at a pH higher than 5.5. Also provided is a method to prepare an anesthetic composition using a simpler and more robust for large-scale manufacture and for providing a high molar ratio of local anesthetic agent to phospholipid content as compared to the prior art. This anesthetic composition has a prolonged duration of efficacy adapted to drug delivery.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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