University of Louisville Research Foundation; Inc.
发明人:
Jill Steinbach-Rankins,Kenneth Palmer
申请号：
US15180963
公开号：
US20160361382A1
申请日:
2016.06.13
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A composition is provided comprising an electrospun fiber having a surface with a biological adhesive moiety conjugated to the surface of the electrospun fiber. The biological adhesive moiety included in the composition can be a lectin such as griffithsin. The composition can further include an effective amount of an antiviral agent encapsulated by an electrospun fiber. Nanoparticles including a microbicide conjugated to the surface of the nanoparticle can also be included in the composition. Methods of treating a viral infection are also provided and include administering to a subject an effective amount of a composition comprising an electrospun fiber having a surface and a biological adhesive moiety conjugated to the surface of the electrospun fiber.
