Example embodiments of the present invention include compositions, materials, and methods that provide a single component tooth root sealer. The single component tooth root sealer can be designed to moisture cure at temperatures found within the human mouth. Examples of the single component tooth root sealer can include silicone compositions, such as condensation silicones of the alkoxy, acetoxy, and oxime type. Further examples of the single component tooth root sealer can include UV/visible light-initiators, antimicrobial agents, and radio-opaque compounds.
