The embodiment of the proposed invention relates a midazolam containing prefilled syringe for administration of midazolam with retained effective sterility. The present prefilled syringes are filled with midazolam while manufacturing and can be readily administered for general anesthesia or procedural sedation or other indications without filling the syringe from the midazolam vial. Therefore, there are no chances of contamination unlike the conventional ways that include the filling of syringe from the midazolam vials prior to administration. The elimination of vials reduces the overall costs including the costs of manufacturing, handling, storage, transportation etc. The cumbersome separate handling of syringes and vials is also not required. The present invention also facilitates considerable reduction in medical wastage as no vials are used and to contribute to medical waste.
