Provided are a novel, percutaneously-absorbed pharmaceutical composition for external application and a method for manufacturing the same. The composition is a pharmaceutical composition, for external application, formed by formulating a fatty acid ester and a fatty acid glycerol ester into an organic gel. More specifically, the composition is formed by using a medicament such as a non-anesthetic analgesic as an active ingredient, and combining it with a fatty acid ester and a fatty acid glycerol ester to form the state of an organic gel. The pharmaceutical composition of the present invention significantly improves the skin permeability of a medicament such as a non-anesthetic analgesic, and it is capable of allowing a sufficient amount of medicament to continuously permeate the skin. Since the pharmaceutical composition is in the state of an organic gel, it is readily applicable to a usable preparation. Further, the pharmaceutical composition has high drug release rate, and it can be used to achieve effective use of a medicament. Thus, the pharmaceutical composition is highly useful.本發明是關於一種新穎的經皮吸收型的外用醫藥組成物及其製造方法，該組成物係調配脂肪酸酯及脂肪酸甘油酯而成的有機凝膠的外用醫藥組成物，更詳細地說明，係以非麻藥性鎮痛藥等的藥劑為有效成分，並配合脂肪酸酯及脂肪酸甘油酯而成之有機凝膠形態。本發明外用醫藥組成物顯著改善非麻藥性鎮痛藥等藥劑的皮膚透過性，可以使充分量的藥劑持續性地透過皮膚，且因是有機凝膠的形態，容易應用於實用性的製劑。又，由於具有高的藥劑釋放率，可以謀求藥劑的有效利用等，是有用性高的組成物。
