PROCEDE PERMETTANT DE DETERMINER UN SCHEMA DE CHIMIOTHERAPIE BASE SUR L'EXPRESSION D'UNE GLUTATHIONE-S-TRANSFERASE PI

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专利权人:

RESPONSE GENETICS; INC.

发明人:

DANENBERG, KATHLEEN D.

申请号：

CA2450257

公开号：

CA2450257C

申请日:

2002.05.15

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

The present invention relates to prognostic methods which are useful inmedicine, particularly cancer chemotherapy. The object of the invention toprovide a method for assessing GST -pi expression levels in fixed or fixed andparaffin embedded tissues and prognosticate the probable resistance orsensitivity of a patient's tumor to treatment with platinum-based therapies byexamination of the amount of GST -pi mRNA in a patient's tumor cells andcomparing it to a predetermined threshold expression level. More specifically,the invention provides to oligonucleotide primer pair GST-piand methodscomprising their use for detecting levels of GST-pi mRNA.

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中国工程科技知识中心

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http://www.ckcest.cn/home/