PROCEDE DE FABRICATION DE POLYPEPTIDES EXEMPTS DE METHIONINE N-TERMINALE DANS DES CELLULES HOTES MICROBIENNES

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专利权人:

BIOCON LIMITED

发明人:

SASTRY, KEDARNATH,SRIRAM, AKUNDI VENKATA,GOEL, ANUJ,KAMATH, SANDEEP VISHWANATH,VALERA, HARDIK,GARG, MAYANK KUMAR,SREENIVAS, SUMA,SWETHA, MALUR DATTATREYA,BASU, AMRITA,RAGHUNANDAN, REENA NICHINMETLA

申请号：

EP07706183

公开号：

EP2097520A4

申请日:

2007.01.12

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

A method of making N-terminal methionine free polypeptide in a recombinant microbial host cell and pharmaceutical compositions along with one or more pharmaceutical excipients for management of various therapeutic disorders. Specifically, the invention relates to the production of N-terminal methionine free Streptokinase or human growth hormone by co expression with a protease enzyme in E.coli.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/