Hidtil ukendte peptider til behandling og forebyggelse af immunrelaterede sygdomme, herunder behandling og forebyggelse af infektion ved modulering af naturlig immunitet
DONINI, Oreola,ROZEK, Annett,LENTZ, Shannon, Wayne
申请号：
DK10003191
公开号：
DK2236608T3
申请日:
2006.10.04
申请国别(地区):
DK
年份:
2017
代理人:
摘要：
In one aspect, the present invention provides isolated novel peptides that can be used to modulate innate immunity in a subject. and/or for the treatment of an immune-related disorder, including treating and preventing infection by modulating innate immunity. Also provided are an agent reactive with the peptide, a pharmaceutical composition that includes the peptide, an isolated nucleic acid molecule encoding the peptide, a recombinant nucleic acid construct that includes the nucleic acid molecule, at least one host cell comprising the recombinant nucleic acid construct, and a method of producing the peptide using the host cell. The present invention further provides a method for treating and/or preventing infection in a subject by administering the peptide of the invention to the subject, thereby modulating innate immunity in the subject. Additionally, the present invention provides a method for predicting whether a subject would be responsive to treatment with a peptide of the invention.
